Artretyzm i reumatoidalne zapalenie stawów
Osteoarthritis and rheumatoid arthritis
- Osteoarthritis occurs when your body can no longer properly repair the wear-and-tear that occurs in your joints from using them on a daily basis. Over time, the cartilage at the ends of your bones starts to wear out, which prevents your joints from moving smoothly, causing pain and inflammation. Osteoarthritis is also known as degenerative joint disease.
- Rheumatoid arthritis on the other hand, is an autoimmune disease in which your own immune system attacks your own tissues, in this case, your joints. This causes chronic inflammation, painful swelling, and and can lead to joint deformity.
How joints work and what can go wrong
What are the signs and symptoms of arthritis?
|Deep, achy joint pain that worsens with movement and activity.||Tender, warm, swollen, painful joints.|
|Loss of flexibility, especially if you have been stationary for a while.||Morning stiffness that may last for several hours.|
|Bony lumps around the joint.||A general feeling of being tired and unwell, which may be accompanied by fever and weight loss.|
What factors predispose you to arthritis?
|Age - can occur at any age, but is most common after the age of 60.||Age - can occur at any age, but most commonly begins between 40 and 60 years of age.|
|Gender - more common in women than men.||Gender - more common in women than in men.|
|Family history - tends to run in families.||Family history - tends to run in families.|
How common is arthritis?
Can arthritis be prevented?
- Losing some weight - if you are over your recommended weight, try to lose a bit; extra weight puts a lot of extra stress on your joints.
- Staying active - moderate exercise can help increase your range of motion, and the strength and endurance of your muscles, which helps keep your joints more stable.
- Heat or ice - may provide temporary relief of pain and swelling, but make sure to ask for guidance from a healthcare professional first.
- Protecting your joints - adjust your lifestyle to avoid putting your joints under unnecessary stress.
What treatments are available for arthritis?
Weź pod uwagę:
- Obesity is an important risk factor for osteoarthritis. Why do you think that might be? Most obese patients will have knee joint deformities that cause misalignment of the joint, which alters the load distribution on the knee and accelerates cartilage composition and degeneration. The increase in force on the knee and hip joints is probably the primary reason that these joints are more susceptible to osteoarthritis. However, new research is also showing that fat cells may play an important role in regulating bone and cartilage metabolism in joints, and this gets out of balance if you are obese.
- Biologics are used when other treatments are unable to effectively control inflammation. The high cost of these of these drugs has raised concerns about whether or not they will be available for everyone who needs them. Two recent developments may address these concerns. What do you think they might be? 1) Using aggressive combination treatments including biologics at first to gain good control of inflammation in patients with recent-onset rheumatoid arthritis appears to pave the way for effective maintenance therapy with the cheaper conventional drugs - this approach has been used in the treatment of cancer, and is known as “induction-maintenance” treatment. 2) Dosing-down of biologics in patients with established rheumatoid arthritis appears to continue to provide effective disease control at much lower cost.